Each application of Ortho-Gynol Contraceptive jelly contains 150mg of Nonoxynol-9 which provides effective protection against pregnancy when used as directed. Ortho-Gynol Contraceptive Jelly is clear, unscented, water-soluble and greaseless. Each box contains one tube (108gm) of contraceptive jelly, and one applicator. Ortho-Gynol Contraceptive jelly may be used with a diaphragm or condom. When used with a diaphragm, the jelly is effective for up to six hours. An additional application is required if intercourse takes place repeatedly or more than six hours after initial insertion. Always read product instructions before use.